PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING BONE DISEASE COMPRISING AMINOBENZOATE DERIVATIVES

摘要

PURPOSE: A pharmaceutical composition for preventing and treating bone diseases is provided to promote differentiation and mineralization of osteoblast and to promote osteoporosis, thereby being used as a pharmaceutical composition and a health food composition for preventing or treating osteoporosis. CONSTITUTION: A pharmaceutical composition for preventing or treating bone diseases contains aminobenzoate derivatives of chemical formula 1 or a pharmaceutically acceptable salt thereof. The compound of chemical formula 1 is selected among methyl 4-aminobenzoate, isopropyl 4-aminobenzoate, butyl 4-aminobenzoate, butyl 4-acetamidobenzoate, butyl 4-benzamido benzoate, butyl 4-(nicotine amido)benzoate, and butyl 4-(morpholine-4-carboxamido)benzoate. The composition promotes differentiation or activation of osteoblast.