发明名称 |
SELECTIVE BINDING OF PATHOLOGICAL FORMS OF PRION PROTEINS USING POLYIONIC POLYMERS |
摘要 |
Infective aggregating forms of proteins such as PrP, amyloid, and tau are bound selectively in the presence of the normal form protein using a polyionic binding agent such as dextran sulphate or pentosan (anionic), or polyamine compounds such as pDADMAC (cationic) under selective binding conditions including the use of n-lauroylsarcosine at mildly alkaline pH, and may then be assayed.
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申请公布号 |
CA2477569(C) |
申请公布日期 |
2013.09.24 |
申请号 |
CA20032477569 |
申请日期 |
2003.02.28 |
申请人 |
MICROSENS BIOPHAGE LIMITED |
发明人 |
LANE, AMIN REZA;STANLEY, CHRISTOPHER J.;WILSON, STUART MARK |
分类号 |
G01N33/68;C07K1/22;C07K14/47;C08B37/02;G01N33/53 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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