发明名称 |
METHOD FOR IDENTIFICATION OF ONCOGENE, METHOD FOR ESTABLISHMENT OF CELL CAPABLE OF EXPRESSING ONCOGENE, AND METHOD FOR SCREENING FOR ONCOGENE-TARGETING SUBSTANCE |
摘要 |
The present invention provides a methodology that can develop a more excellent anti-cancer drug than conventional ones for various cancers. Specifically, the present invention provides a method for establishing an artificial cell, comprising treating a cancer cell with an expression vector for a foreign oncogene and then culturing the cancer cell treated with the expression vector under a condition which inhibits an expression or function of an oncogene that is inherent to the cancer cell, and an established artificial cell; a method of screening an anti-cancer drug, comprising evaluating whether or not a test substance inhibits a proliferation of the artificial cell; as well as a method for identifying an oncogene, comprising treating a cancer cell with an expression vector for a test gene and then culturing the cancer cell treated with the expression vector under a condition which inhibits an expression or function of an oncogene that is inherent to the cancer cell. |
申请公布号 |
EP2540822(A4) |
申请公布日期 |
2013.09.11 |
申请号 |
EP20110744793 |
申请日期 |
2011.02.21 |
申请人 |
FUJIREBIO INC. |
发明人 |
ISE, NOBUYUKI;OMI, KAZUYA;NAMBARA, DAISUKE |
分类号 |
C12N5/10;C12N15/09;C12Q1/02;C12Q1/48;C12Q1/68 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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