| 摘要 |
<p>The present invention relates to certain alkyl- and di-substituted amido-benzyl sulfonamide compounds, pharmaceutical compositions comprising such compounds, and to methods of treatment of NAMPT-mediated disorders, such as diabetes, rheumatoid arthritis, atherosclerosis, sepsis, inflammation and cancers comprising administering a theraputically effective amount of the amido-benzyl sulfonamide compound to a subject in need of treatment.</p> |
| 申请人 |
GENENTECH, INC.;FORMA TM, LLC |
发明人 |
BAIR, KENNETH, W.;BAUMEISTER, TIMM, R.;BUCKMELTER, ALEXANDRE, J.;CLODFELTER, KARL, H.;GUNZNER-TOSTE, JANET;HAN, BINGSONG;LIN, JIAN;REYNOLDS, DOMINIC, J.;SMITH, CHASE, C.;WANG, ZHONGGUO;ZAK, MARK;ZHENG, XIAOZHANG;ZHAO, GUILING |
