发明名称 ENDOGENOUS RETROVIRUS UP-REGULATED IN PROSTATE CANCER
摘要 PROBLEM TO BE SOLVED: To provide a method for diagnosing prostate cancer, comprising a step of detecting the presence or absence of an expression product of a HML-2 endogenous retrovirus in a patient sample.SOLUTION: Human endogenous retroviruses of the HML-2 family show up-regulated expression in prostate tumors. This finding can be used in prostate cancer screening, diagnosis and therapy. There is provided a method for diagnosing cancer, especially prostate cancer, the method comprising the step of detecting the presence or absence of an expression product of a HML-2 endogenous retrovirus in a patient sample. Higher levels of expression product relative to normal tissue indicate that the patient from whom the sample has been taken has cancer.
申请公布号 JP2013165722(A) 申请公布日期 2013.08.29
申请号 JP20130068150 申请日期 2013.03.28
申请人 NOVARTIS VACCINES & DIAGNOSTICS INC 发明人 GARCIA PABLO;HARDY STEPHEN F;WILLIAMS LEWIS T;ESCOBEDO JAIME
分类号 C12Q1/68;G01N33/53;A61K31/7088;A61K38/00;A61K39/00;A61K39/395;A61K45/00;A61K48/00;A61P3/10;A61P13/08;A61P15/00;A61P25/00;A61P35/00;C07K14/08;C07K14/15;C07K16/10;C12N7/00;C12N15/09;C12P21/08;C12Q1/02;C12Q1/70;G01N33/543;G01N33/569;G01N33/574;G01N33/577 主分类号 C12Q1/68
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