发明名称 |
ENDOGENOUS RETROVIRUS UP-REGULATED IN PROSTATE CANCER |
摘要 |
PROBLEM TO BE SOLVED: To provide a method for diagnosing prostate cancer, comprising a step of detecting the presence or absence of an expression product of a HML-2 endogenous retrovirus in a patient sample.SOLUTION: Human endogenous retroviruses of the HML-2 family show up-regulated expression in prostate tumors. This finding can be used in prostate cancer screening, diagnosis and therapy. There is provided a method for diagnosing cancer, especially prostate cancer, the method comprising the step of detecting the presence or absence of an expression product of a HML-2 endogenous retrovirus in a patient sample. Higher levels of expression product relative to normal tissue indicate that the patient from whom the sample has been taken has cancer. |
申请公布号 |
JP2013165722(A) |
申请公布日期 |
2013.08.29 |
申请号 |
JP20130068150 |
申请日期 |
2013.03.28 |
申请人 |
NOVARTIS VACCINES & DIAGNOSTICS INC |
发明人 |
GARCIA PABLO;HARDY STEPHEN F;WILLIAMS LEWIS T;ESCOBEDO JAIME |
分类号 |
C12Q1/68;G01N33/53;A61K31/7088;A61K38/00;A61K39/00;A61K39/395;A61K45/00;A61K48/00;A61P3/10;A61P13/08;A61P15/00;A61P25/00;A61P35/00;C07K14/08;C07K14/15;C07K16/10;C12N7/00;C12N15/09;C12P21/08;C12Q1/02;C12Q1/70;G01N33/543;G01N33/569;G01N33/574;G01N33/577 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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