| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a toxicity testing method which enables the replacement of an acute toxicity test with respect to various drugs or food materials of a mammal having not only a problem of economical efficiency or labor but also a moral problem without bringing about a problem from an aspect of cost and morals and reducing the meaning of the test. <P>SOLUTION: The toxicity testing method is a method for evaluating the acute toxicity of the mammal by an examination target showing cytotoxicity with respect to the mammal and performed by administering the examination target to the larva of a holometabolous insect to calculate the LD 50 value of the larva. Further, this toxicity testing method is performed by measuring the metabolic state of the examination target in the larva of the holometabolous insect to which the examination target is administered. <P>COPYRIGHT: (C)2009,JPO&amp;INPIT</p> |
