发明名称 FLUOROALKOXY-SUBSTITUTED 1,3-DIHYDRO-ISOINDOLYL COMPOUND AND ITS PHARMACEUTICAL USE
摘要 PROBLEM TO BE SOLVED: To provide pharmaceutical compositions for treatment or prevention of diseases associated with PDE4 (cyclic nucleotide phosphodiesterase 4).SOLUTION: Pharmaceutical compositions contain fluoroalkoxy-substituted 1,3-dihydro-isoindolyl compounds, represented by 3-(4-acetylamino-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3-cyclopropylmethoxy-4-difluoromethoxy-phenyl)-propionic acid, pharmaceutically acceptable salts, hydrates, solvates, clathrates, enantiomers, diastereomers, racemates, or mixtures of stereoisomers thereof.
申请公布号 JP2013151497(A) 申请公布日期 2013.08.08
申请号 JP20130026432 申请日期 2013.02.14
申请人 CELGENE CORP 发明人 MULLER GEORGE W;MAN HON-WAH;ZHANG WEIHONG
分类号 A61K31/4035;A61K;A61K6/00;A61K31/4178;A61K31/425;A61K31/4709;A61K31/5377;A61K45/00;A61P1/04;A61P1/16;A61P9/10;A61P11/00;A61P17/00;A61P17/06;A61P19/00;A61P19/02;A61P25/00;A61P27/02;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;A61P35/02;A61P37/06;A61P37/08;A61P43/00;C07D209/44;C07D209/46;C07D209/48;C12N9/99 主分类号 A61K31/4035
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