Naloxol-polyethylene glycol conjugates of the formula: are provided in oxalate or phosphate salt forms including crystalline forms. Methods of preparing the salt forms and pharmaceutical compositions comprising the salt forms are also provided.
申请公布号
EP2621496(A1)
申请公布日期
2013.08.07
申请号
EP20110829686
申请日期
2011.09.29
申请人
ASTRAZENECA AB;NEKTAR THERAPEUTICS
发明人
AASLUND, BENGT LEONARD;AURELL, CARL-JOHAN;BOHLIN, MARTIN HANS;SEBHATU, TESFAI;YMEN, BO INGVAR;HEALY, ERIC THOMAS;JENSEN, DAVID RICHARD;JONAITIS, DAVID THOMAS;PARENT, STEPHAN