发明名称 |
Treatment of ectodermal dysplasia with EDA1 fusion proteins |
摘要 |
Disclosed is a recombinant fusion protein containing an amino-acid sequence which comprises: (a) the Fc section or part of an Fc section of an immunoglobulin as component (A) or a functional variant of component (A); (b) the extracellular part of a TNF ligand or a partial sequence of the extracellular part of a TNF ligand as component (B) or a functional variant of component (B); and optionally (c) a transition area between component (A) and component (B), containing a linker.
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申请公布号 |
US8501177(B2) |
申请公布日期 |
2013.08.06 |
申请号 |
US20100756268 |
申请日期 |
2010.04.08 |
申请人 |
GAIDE OLIVIER;SCHNEIDER PASCAL;TSCHOPP JURG;TOPOTARGET SWITZERLAND SA |
发明人 |
GAIDE OLIVIER;SCHNEIDER PASCAL;TSCHOPP JURG |
分类号 |
A61K39/395;A61K38/00;C07K14/705 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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