发明名称 Methods and reagents for efficient and targeted delivery of therapeutic molecules to CXCR4 cells
摘要 The invention relates to conjugates comprising a targeting moiety specific for the CXCR4 based on the polyphemusin-derived peptide and a therapeutic or imaging agent. The invention relates as well to the application of said conjugates for the therapy and diagnostics which require the specific targeting to CXCR4+ cells.
申请公布号 AU2012206533(A1) 申请公布日期 2013.08.01
申请号 AU20120206533 申请日期 2012.01.13
申请人 CENTRO INVESTIGACION BIOMEDICA EN RED (CIBER BBN);INSTITUT RECERCA HOSPITAL DE LA SANTA CREU I SANTPAU;UNIVERSITAT AUTONOMA DE BARCELONA 发明人 VILLAVERDE CORRALES, ANTONIO;VAZQUEZ GOMEZ, ESTHER;CESPEDES NAVARRO, MARIA VIRTUDES;CASANOVA RIGAT, ISOLDA;FERRER MIRALLES, NEUS;MANGUES BAFALLUY, RAMON;UNZUETA ELORZA, UGUTZ
分类号 C07K14/435;A61K47/48;C12N15/62 主分类号 C07K14/435
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