发明名称 INCLUSION COMPLEXES COMPRISING PIROXICAM, A CYCLODEXTRIN AND ARGININE
摘要 <p>Soluble inclusion complex comprising one or several active substances difficult to dissolve in aqueous medium including one or several host molecules and piroxicam-cyclodextrin-arginine in which the level of solubilization of piroxicam in solution containing 4 g/liter piroxicam in water, measured at 37[deg]C with agitation over 5-120 minutes is higher than 90%, most especially higher than 99%. INDEPENDENT CLAIM are included for: (1) preparation of the complex involving:contact with host molecules, initation of molecular diffusion, recovery of the soluble inclusion compound formed; (2) a pharmaceutical composition containing the complex.</p>
申请公布号 PT2260871(E) 申请公布日期 2013.08.01
申请号 PT20100182089T 申请日期 2005.03.29
申请人 PIERRE FABRE MEDICAMENT 发明人 BERNARD FREISS;FLORENCE MARCIACQ;HUBERT LOCHARD
分类号 A61K47/48;A61P29/00;B82Y5/00 主分类号 A61K47/48
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