Method for determining a probability of a major adverse cardiac event (MACE)

摘要

Embodiments of the present invention provide A method of determining a likelihood of a major adverse cardiac event (MACE) of a subject within a predetermined period of time, comprising determining a presence of electrocardiographic (ECG) ischemia of said subject, observing a presence of vomiting, sweating, hypotension and worsening angina of the subject, determining quantities of heart-type fatty acid binding protein (H-FABP) and troponin (Tn) in a sample taken from said subject, determining a probability value P indicative of a likelihood of a MACE of the subject within a predetermined period of time, wherein P is calculated based on the quantities of H-FABP and Tn and values indicative of the presence of each of the ECG ischemia, pain radiating to the right arm or shoulder, vomiting, sweating, hypotension and worsening angina of the patient.