发明名称 |
TREATMENT OF HEART FAILURE AND SUDDEN CARDIAC DEATH |
摘要 |
<p>A method of reducing heart failure or preventing sudden cardiac death in a subject in need thereof is carried out by administering a composition comprising a compound that increases cellular level of Sarco/endoplasmic reticulum Ca2+-ATPase 2a (SERCA2a). The invention represents a significant breakthrough in the treatment or prevention of chronic heart failure. The invention is based upon the discovery that a Mifepristone molecule increases the cellular level of SERCA2a protein.</p> |
申请公布号 |
WO2013103687(A2) |
申请公布日期 |
2013.07.11 |
申请号 |
WO2013US20102 |
申请日期 |
2013.01.03 |
申请人 |
RHODE ISLAND HOSPITAL;KOREN, GIDEON;ZHENG, ZHE |
发明人 |
KOREN, GIDEON;ZHENG, ZHE |
分类号 |
A61K31/58 |
主分类号 |
A61K31/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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