发明名称 |
SYNTHETIC ANALOGUES OF PHOSPHATIDYL-MYO-INOSITOL MANNOSIDES WITH AN INHIBITORY ACTIVITY ON THE INFLAMMATORY RESPONSE |
摘要 |
<p>The present invention relates to novel synthetic analogs of phosphatidyl-myo-inositol mannosides (hereinafter referred to as PIMs) of general formula (I): or a pharmaceutically acceptable salt thereof, to the method for preparing same and to the use thereof in the prevention or treatment of a disease associated with the overexpression of cytokines or of chemokines, in particular of TNF and/or of IL-12. The invention also relates to a pharmaceutical composition comprising at least one synthetic derivative of PIM.</p> |
申请公布号 |
EP2280986(B1) |
申请公布日期 |
2013.07.10 |
申请号 |
EP20090765996 |
申请日期 |
2009.05.20 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S);UNIVERSITE D'ORLEANS |
发明人 |
QUESNIAUX RYFFEL, VALERIE;MARTIN, OLIVIER;FRONT, SOPHIE |
分类号 |
C07H15/207;A61K31/7034;A61P29/00;A61P31/00;A61P37/00 |
主分类号 |
C07H15/207 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|