发明名称 |
The use of BNP-type peptides for predicting the need for dialysis |
摘要 |
<p>The present invention relates to diagnosing the risk of developing a need for dialysis and/or predicting a need for dialysis, particularly in patients suffering from renal disorders. More particularly, the present invention relates to diagnosing the risk of developing a need for dialysis in a patient, comprising the steps of (a) measuring the level of a BNP-typc peptide or a variant thereof in a sample from the patient, (b) diagnosing the risk by comparing the measured level of the BNP-type peptide or a variant thereof to at least one reference level. The BNP-type peptide may for example be brain natriuretic peptide (BNP) or the N-terminal fragment of BNP, NT-proBNP. A need for dialysis can be present in patients suffering from any kind of renal disorder, e.g. in patients suffering from diabetes or chronic kidney disease. A need for dialysis may also include a need for any other kind of renal replacement therapy, including kidney transplantation or renal tissue transplantation.</p> |
申请公布号 |
EP1970709(B1) |
申请公布日期 |
2013.07.10 |
申请号 |
EP20070103577 |
申请日期 |
2007.03.06 |
申请人 |
ROCHE DIAGNOSTICS GMBH;F. HOFFMANN-LA ROCHE AG |
发明人 |
HERMANN, ZUZANA;AMANN-ZALAN, ILDIKO;MOECKS, JOACHIM;BURGER, HANS ULRICH;ESCRIG, CAESAR;SCHERHAG, ARMIN;DOUGHERTY, FRANK CH. |
分类号 |
G01N33/68 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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