发明名称 |
SCREENING METHOD FOR ANTIDIABETIC AGENT USING NEWLY IDENTIFIED INSULIN SECRETION REGULATION FACTOR |
摘要 |
<p>It is an object of the present invention to provide a newly identified insulin secretion regulation factor that can control blood sugar in the normal range, and a method for screening an antidiabetic drug using said factor. In accordance with the present invention, there is provided a composition which is (i) a protein comprising an amino acid sequence represented by SEQ ID NO: 2 or SEQ ID NO: 4; or (ii) a protein comprising an amino acid sequence in which one or several amino acids are deleted, substituted or added in an amino acid sequence represented by SEQ ID NO: 2 or SEQ ID NO: 4 and negatively regulating insulin secretion, as well as a method for screening antidiabetic drug using said protein or a nucleic acid encoding the same.</p> |
申请公布号 |
EP2612678(A1) |
申请公布日期 |
2013.07.10 |
申请号 |
EP20110821972 |
申请日期 |
2011.09.02 |
申请人 |
TOKYO INSTITUTE OF TECHNOLOGY |
发明人 |
IMAI, TAKESHI;HANDA, HIROSHI |
分类号 |
A61K38/45;A01K67/027;A61K38/16;A61K48/00;A61P3/10;C07K14/47;C12N5/10;C12Q1/02;G01N33/15;G01N33/50 |
主分类号 |
A61K38/45 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|