发明名称 |
COMPOSITIONS AND METHODS FOR MODIFYING A PREDETERMINED TARGET NUCLEIC ACID SEQUENCE |
摘要 |
Provided herein are compositions and methods for modifying a predetermined nucleic acid sequence. A programmable nucleoprotein molecular complex containing a polypeptide moiety and a specificity conferring nucleic acid (SCNA) which assembles in-vivo, in a target cell, and is capable of interacting with the predetermined target nucleic acid sequence is provided. The programmable nucleoprotein molecular complex is capable of specifically modifying and/or editing a target site within the target nucleic acid sequence and/or modifying the function of the target nucleic acid sequence. |
申请公布号 |
CA2858801(A1) |
申请公布日期 |
2013.06.20 |
申请号 |
CA20122858801 |
申请日期 |
2012.12.16 |
申请人 |
TARGETGENE BIOTECHNOLOGIES LTD |
发明人 |
SHIBOLETH, YOEL MOSHE;WEINTHAL, DAN MICHAEL |
分类号 |
A61K31/7105;A61K31/711;A61K31/7115;A61K31/712;A61K31/7125;A61K31/713;A61K48/00;C12N5/10;C12N15/62 |
主分类号 |
A61K31/7105 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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