发明名称 HETERO RING COMPOUND
摘要 <p>[Problem] A novel and excellent compound which is useful as an agent for preventing and/or treating rejection reactions in various organ transplantations, allergy diseases, autoimmune diseases, and hematologic tumor, and based on a PI3K´ selective inhibitory action and/or an IL-2 production inhibitory action and/or a B cell proliferation inhibitory action (including an activation inhibitory action). [Means for Solution] The present inventors have investigated a compound having a PI3K´ selective inhibitory action and/or an IL-2 production inhibitory action and/or a B cell proliferation inhibitory action (including an activation inhibitory action), and have found that the heterocyclic compound of the present invention has a PI3K´ selective inhibitory action and/or and IL-2 production inhibitory action and/or a B cell proliferation inhibitory action (including an activation inhibitory action), thereby completing the present invention.</p>
申请公布号 EP2604601(A1) 申请公布日期 2013.06.19
申请号 EP20110816426 申请日期 2011.08.09
申请人 ASTELLAS PHARMA INC. 发明人 TAKAHASHI, FUMIE;IMADA, SUNAO;ASANO, TORU;KOZUKI, YOSHIHIRO;MAEDA, JUNKO;KATO, KOJI;FUKAHORI, HIDEHIKO
分类号 C07D401/14;A61K31/5377;A61K31/541;A61K31/55;A61P1/04;A61P11/06;A61P17/06;A61P19/02;A61P29/00;A61P35/02;A61P37/02;A61P37/06;A61P37/08;A61P43/00 主分类号 C07D401/14
代理机构 代理人
主权项
地址