发明名称 |
HETERO RING COMPOUND |
摘要 |
<p>[Problem] A novel and excellent compound which is useful as an agent for preventing and/or treating rejection reactions in various organ transplantations, allergy diseases, autoimmune diseases, and hematologic tumor, and based on a PI3K´ selective inhibitory action and/or an IL-2 production inhibitory action and/or a B cell proliferation inhibitory action (including an activation inhibitory action). [Means for Solution] The present inventors have investigated a compound having a PI3K´ selective inhibitory action and/or an IL-2 production inhibitory action and/or a B cell proliferation inhibitory action (including an activation inhibitory action), and have found that the heterocyclic compound of the present invention has a PI3K´ selective inhibitory action and/or and IL-2 production inhibitory action and/or a B cell proliferation inhibitory action (including an activation inhibitory action), thereby completing the present invention.</p> |
申请公布号 |
EP2604601(A1) |
申请公布日期 |
2013.06.19 |
申请号 |
EP20110816426 |
申请日期 |
2011.08.09 |
申请人 |
ASTELLAS PHARMA INC. |
发明人 |
TAKAHASHI, FUMIE;IMADA, SUNAO;ASANO, TORU;KOZUKI, YOSHIHIRO;MAEDA, JUNKO;KATO, KOJI;FUKAHORI, HIDEHIKO |
分类号 |
C07D401/14;A61K31/5377;A61K31/541;A61K31/55;A61P1/04;A61P11/06;A61P17/06;A61P19/02;A61P29/00;A61P35/02;A61P37/02;A61P37/06;A61P37/08;A61P43/00 |
主分类号 |
C07D401/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|