| 发明名称 |
IMPROVED ASPARTYL-TRNA SYNTHETASES |
| 摘要 |
<p>The present invention provides aspartyl-tRNA synthetase derived proteins (DRS polypeptides) with altered cysteine content, compositions comprising the same, and methods of using such polypeptides and compositions for treating or diagnosing a variety of conditions. The DRS polypeptides of the invention have immunomodulatory properties, and exhibit improved activity and stability.</p> |
| 申请公布号 |
WO2013086216(A1) |
申请公布日期 |
2013.06.13 |
| 申请号 |
WO2012US68282 |
申请日期 |
2012.12.06 |
| 申请人 |
ATYR PHARMA, INC. |
发明人 |
BUECHLER, YING JI;WU, CHI-FANG;ADAMS, RYAN ANDREW;PIEHL, KRISTI HELEN;GREVE, JEFFREY;MENDLEIN, JOHN D. |
| 分类号 |
C12N9/00;A61K38/43;A61P35/00;C07K19/00;C12N15/52;C12N15/63 |
主分类号 |
C12N9/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
