发明名称 |
Process for preparation of 2-fluoroacrylic esters |
摘要 |
According to the present invention, there is provided a production process of a 2-fluoroacrylic ester including: a bromination step of converting a 2-fluoropropionic ester to a 2-bromo-2-fluoropropionic ester by reaction of the 2-fluoropropionic ester with a nitrogen-bromine bond-containing brominating agent in the presence of a radical initiator; and a dehydrobromination step of reacting the 2-bromo-2-fluoropropionic ester with a base. It is not necessary in this process to adopt very-low-temperature conditions and to use a stoichiometric amount of expensive reagent. The target 2-fluoroacrylic ester can be thus produced at low cost.
|
申请公布号 |
US8450520(B2) |
申请公布日期 |
2013.05.28 |
申请号 |
US201013266008 |
申请日期 |
2010.03.23 |
申请人 |
ISHII AKIHIRO;YAMAZAKI TAKAKO;TSURUTA HIDEYUKI;MIYAZAWA SATORU;OOTANI MICHITAKA;OOTSUKA TAKASHI;TAKAHASHI MIKIHIRO;FUJIMOTO MASATAKA;CENTRAL GLASS COMPANY, LIMITED |
发明人 |
ISHII AKIHIRO;YAMAZAKI TAKAKO;TSURUTA HIDEYUKI;MIYAZAWA SATORU;OOTANI MICHITAKA;OOTSUKA TAKASHI;TAKAHASHI MIKIHIRO;FUJIMOTO MASATAKA |
分类号 |
C07C67/287 |
主分类号 |
C07C67/287 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|