发明名称 ANTI-ADRENOMEDULLIN (ADM) ANTIBODY OR ANTI-ADM ANTIBODY FRAGMENT OR ANTI-ADM NON-IG SCAFFOLD FOR USE IN THERAPY OF AN ACUTE DISEASE OR ACUTE CONDITION OF A PATIENT FOR STABILIZINGTHE CIRCULATION
摘要 Patients having a chronic or acute disease or acute condition may be in need for stabilizing the circulation, Subject matter of the present disclosure is an anti-Adrenomedullin (ADM) antibody or an anti-adrenomedullin antibody fragment or an anti-ADM non-lg scaffold for use in therapy of acute disease or condition of a patient for stabilizing the circulation. In a preferred embodiment anti-ADM antibody or an anti-adrenomedullin antibody fragment or an anti-ADM non-lg scaffold according to the present disclosure reduces the vasopressor requirement, e.g. catecholamine requirement of said patient. The catecholamine requirement of a patient is an indicator for the condition of the circulation and hemodynamic function of said patient.
申请公布号 CA2856142(A1) 申请公布日期 2013.05.23
申请号 CA20122856142 申请日期 2012.11.16
申请人 ADRENOMED AG 发明人 BERGMANN, ANDREAS
分类号 C07K16/26;A61K39/395;A61P9/00;A61P13/12;A61P31/00 主分类号 C07K16/26
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