发明名称 |
TECHNIQUE FOR ISOLATING/CULTURING COLORECTAL EPITHELIAL STEM CELL, AND TECHNIQUE FOR TRANSPLANTING COLORECTAL EPITHELIUM EMPLOYING SAID TECHNIQUE |
摘要 |
The purpose of the present invention is to provide: a culture medium for the in vitro culture of a colorectal epithelial stem cell or the like; a method for culturing a colorectal epithelial stem cell or the like in vitro using the culture medium; a prophylactic/therapeutic agent for bowel diseases, which comprises a colorectal epithelial stem cell or the like produced by culturing by the aforementioned method; a method for administering, i.e., transplanting, a colorectal epithelial stem cell or the like produced by culturing by the aforementioned method to a patient suffering from a bowel disease; and a method for isolating a colorectal epithelial stem cell or the like. The culture medium, the prophylactic/therapeutic agent and the methods are characterized by using a culture medium for the in vitro culture of a colorectal epithelial stem cell and/or a colorectal epithelial cell, which comprises serum albumin, Wnt3a and r-spondin-1. |
申请公布号 |
WO2013061608(A1) |
申请公布日期 |
2013.05.02 |
申请号 |
WO2012JP06897 |
申请日期 |
2012.10.26 |
申请人 |
NATIONAL UNIVERSITY CORPOPRATION TOKYO MEDICAL AND DENTAL UNIVERSITY |
发明人 |
WATANABE, MAMORU;NAKAMURA, TETSUYA |
分类号 |
C12N5/071;A61K35/38;A61P1/00;A61P1/04;C12N5/074 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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