发明名称 TECHNIQUE FOR ISOLATING/CULTURING COLORECTAL EPITHELIAL STEM CELL, AND TECHNIQUE FOR TRANSPLANTING COLORECTAL EPITHELIUM EMPLOYING SAID TECHNIQUE
摘要 The purpose of the present invention is to provide: a culture medium for the in vitro culture of a colorectal epithelial stem cell or the like; a method for culturing a colorectal epithelial stem cell or the like in vitro using the culture medium; a prophylactic/therapeutic agent for bowel diseases, which comprises a colorectal epithelial stem cell or the like produced by culturing by the aforementioned method; a method for administering, i.e., transplanting, a colorectal epithelial stem cell or the like produced by culturing by the aforementioned method to a patient suffering from a bowel disease; and a method for isolating a colorectal epithelial stem cell or the like. The culture medium, the prophylactic/therapeutic agent and the methods are characterized by using a culture medium for the in vitro culture of a colorectal epithelial stem cell and/or a colorectal epithelial cell, which comprises serum albumin, Wnt3a and r-spondin-1.
申请公布号 WO2013061608(A1) 申请公布日期 2013.05.02
申请号 WO2012JP06897 申请日期 2012.10.26
申请人 NATIONAL UNIVERSITY CORPOPRATION TOKYO MEDICAL AND DENTAL UNIVERSITY 发明人 WATANABE, MAMORU;NAKAMURA, TETSUYA
分类号 C12N5/071;A61K35/38;A61P1/00;A61P1/04;C12N5/074 主分类号 C12N5/071
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