| 摘要 |
<p>999,388. 2 - Benzyloxy-malonic acid derivatives. SANDOZ PATENTS Ltd. May 7, 1962 [May 10, 1961], No. 17401/62. Heading C2C. The invention comprises compounds of general formula I in which R1 and R2 are alkyl (1-5 C), and X is hydroxy, chlorine, bromine, iodine or OR2; and their preparation by reacting a compound BrCR1(COOR2)2 with an alkali metal benzylate to form the diesters I (X=OR2), which are saponified with an alcoholic solution of an alkali metal hydroxide to the ester-acids I (X=ON), from which the halides are obtainable by known methods.</p> |
