发明名称 |
Method of Producing Microparticles |
摘要 |
A method of producing microparticles having a median diameter up to 100 mum and the microparticles so produced are described. The method includes the steps of providing a solvent having a bioactive dispersed or dissolved therein and a vehicle dissolved therein, carrying out an emulsification in a non-solvent phase to produce an emulsion containing the bioactive and the vehicle in a solvent phase, and evaporating the solvent to leave the microparticles, wherein a mixture of at least two surfactants is employed to stabilize the emulsion and wherein the mixture has a hydrophilic-lipophilic balance (HLB) of up to 8.
|
申请公布号 |
US2013101646(A1) |
申请公布日期 |
2013.04.25 |
申请号 |
US201213705928 |
申请日期 |
2012.12.05 |
申请人 |
THE SCHOOL OF PHARMACY, UNIVERSITY OF LONDON;THE SCHOOL OF PHARMACY, UNIVERSITY OF LONDON |
发明人 |
BASIT ABDUL WASEH;MURDAN SUDAX SHINA;KENDALL RICHARD ANDREW |
分类号 |
A61K9/14;A61K9/16;B01J13/02 |
主分类号 |
A61K9/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|