| 摘要 |
The present invention provides an oil-in-water emulsified composition comprising the following ingredients (A)-(G) characterized by miniaturization of the emulsified particles by means of high pressure emulsification:
(A) salt type drug
(B) hydrophilic nonionic surfactant
(C) N-long chain acyl acidic amino acid mono salt
(D) two or more types of higher fatty acids and alkali that constitutes higher fatty acid soap
(E) higher alcohol
(F) oil component
(G) water. The object of the present invention is to provide an oil-in-water emulsified composition prepared by miniaturizing emulsified particles by means of a high pressure emulsification method, said composition being superior in terms of emulsification stability such that electrolyte salt type drugs can be stably blended in. |
