| 发明名称 |
(R)-N-METHYLNALTREXONE, SYNTHETIC METHOD AND MEDICAL USE OF THE SAME |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method of stereoselectively synthesizing R-MNTX and its intermediate, a medical preparation containing R-MNTX and its intermediate and usage of the same. <P>SOLUTION: Provided is the R-MNTX-containing composition wherein there is no S-MNTX detectable by HPLC at a detection limit of 0.02% and at a quantitative limit of 0.05%. <P>COPYRIGHT: (C)2013,JPO&INPIT |
| 申请公布号 |
JP2013075905(A) |
申请公布日期 |
2013.04.25 |
| 申请号 |
JP20120278391 |
申请日期 |
2012.12.20 |
| 申请人 |
PROGENICS PHARMACEUTICALS INC |
发明人 |
DOSHAN HAROLD D;PEREZ JULIO |
| 分类号 |
A61K31/485;A61P1/04;A61P1/10;A61P1/18;A61P3/02;A61P5/04;A61P7/06;A61P7/08;A61P15/00;A61P19/02;A61P21/00;A61P25/00;A61P25/06;A61P25/20;A61P25/36;A61P29/00;A61P29/02;A61P31/14;A61P31/18;A61P35/00;C07D489/08 |
主分类号 |
A61K31/485 |
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