发明名称 Multimeric conjugate
摘要 The present invention is directed to a multimeric agent and a multimeric conjugate formed from this multimeric agent and a biologically active agent. Said multimeric conjugates have a longer life time in vivo and an increased avidity compared to the unmodified biologically agent. The present invention is further directed to a pharmaceutical or diagnostic composition containing said conjugate as well as to a method of its production. The invention additionally provides the use of said conjugates for the detection, determination, separation and/or isolation of a specific binding partner and for the diagnosis, prophylaxis and treatment of diseases in which the specific binding partner is directly or indirectly involved.
申请公布号 US8426357(B2) 申请公布日期 2013.04.23
申请号 US20080525902 申请日期 2008.02.11
申请人 KRAEHMER RALF;LEENDERS FRANK;FIEDLER ERIK;HEY THOMAS;FIEDLER ULRIKE;FIEDLER MARKUS;CELARES GMBH;SCIL PROTEINS GMBH 发明人 KRAEHMER RALF;LEENDERS FRANK;FIEDLER ERIK;HEY THOMAS;FIEDLER ULRIKE;FIEDLER MARKUS
分类号 A61K38/18;A61K35/00;A61K38/00;A61K47/30;C07K17/02;C07K17/08;C08G63/00;C08G69/00;C08G71/00;C08G73/00;C08G75/00 主分类号 A61K38/18
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