发明名称 |
Multimeric conjugate |
摘要 |
The present invention is directed to a multimeric agent and a multimeric conjugate formed from this multimeric agent and a biologically active agent. Said multimeric conjugates have a longer life time in vivo and an increased avidity compared to the unmodified biologically agent. The present invention is further directed to a pharmaceutical or diagnostic composition containing said conjugate as well as to a method of its production. The invention additionally provides the use of said conjugates for the detection, determination, separation and/or isolation of a specific binding partner and for the diagnosis, prophylaxis and treatment of diseases in which the specific binding partner is directly or indirectly involved. |
申请公布号 |
US8426357(B2) |
申请公布日期 |
2013.04.23 |
申请号 |
US20080525902 |
申请日期 |
2008.02.11 |
申请人 |
KRAEHMER RALF;LEENDERS FRANK;FIEDLER ERIK;HEY THOMAS;FIEDLER ULRIKE;FIEDLER MARKUS;CELARES GMBH;SCIL PROTEINS GMBH |
发明人 |
KRAEHMER RALF;LEENDERS FRANK;FIEDLER ERIK;HEY THOMAS;FIEDLER ULRIKE;FIEDLER MARKUS |
分类号 |
A61K38/18;A61K35/00;A61K38/00;A61K47/30;C07K17/02;C07K17/08;C08G63/00;C08G69/00;C08G71/00;C08G73/00;C08G75/00 |
主分类号 |
A61K38/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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