The present invention relates to a nucleic acid molecule containing a sequence of tricyclo nucleosides joined by internucleoside phosphorothioate linkage. The invention also relates to synthetic antisense oligonucleotides and to methods employing the same.
申请公布号
WO2013053928(A1)
申请公布日期
2013.04.18
申请号
WO2012EP70349
申请日期
2012.10.12
申请人
ASSOCIATION INSTITUT DE MYOLOGIE;UNIVERSITAET BERN;UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6);INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
