The invention is based on a finding that silencing PME-1 gene sensitizes cancer cells for apoptosis-inducing activity of certain small molecule chemotherapeutic agents. Thus, the invention is directed to a respective combination therapy, sensitization method and pharmaceutical compositions.
申请公布号
WO2012175798(A3)
申请公布日期
2013.04.11
申请号
WO2012FI50618
申请日期
2012.06.15
申请人
TURUN YLIOPISTO;WESTERMARCK, JUKKA;ERIKSSON, JOHN;KAUR, AMANPREET;PEUHU, EMILIA