| 摘要 |
<p num="1"><br/> The present invention relates to compounds <br/>of the formula (I), wherein R1/R1'' are hydrogen or methyl; X <br/>is -C(O)N(CH3)- or -N(CH3)C(O)-; and to pharmaceutically <br/>acceptable acid addition salts thereof for the treatment of <br/>numerous inflammatory conditions, migraine, rheumatoid <br/>arthritis, asthma, inflammatory bowel disease, mediation of <br/>the emetic reflex, Parkinson''s disease, anxiety, depression, <br/>psychosis, motion sickness, induced vomiting, pain, <br/>headache, migraine, Alzheimer''s disease, multiple sclerosis, <br/>attenuation of morphine withdrawal, cardiovascular changes, <br/>oedema, such as oedema caused by thermal injury, chronic<br/>inflammatory diseases such as rheumatoid arthritis, asthma/bronchial <br/>hyperreactivity and other respiratory diseases including<br/>allergic rhinitis, inflammatory diseases of the gut including ulcerative <br/>colitis and Crohn''s disease, ocular injury and ocular<br/>inflammatory diseases, traumatic brain injury, motion sickness, emesis and <br/>psychoimmunologic or psychosomatic disorders.<br/>
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