| 发明名称 |
Salts and polymorphs of sulfamide NS3 inhibitors |
| 摘要 |
<p>The invention provides new salts and polymorphs of (5R,8S)-7-[(2S)-2- {[(2S)-2-cyclohexyl-2-({[(2S)-1-isopropylpiperidin-2-yl]carbonyl}amino)acetyl]amino}-3,3-dim ethylbutanoyl]-N-{(1R,2R)-2-ethyl-1-[(pyrrolidin-1-ylsulfonyl)carbamoyl]cyclopropyl}-10,10- dimethyl-7-azadispiro[3.0.4.1]decane-8-carboxamide (referred to herein as Compound X), pharmaceutical compositions containing them and processes for their manufacture and use in therapy.</p> |
| 申请公布号 |
AU2011313665(A1) |
申请公布日期 |
2013.03.28 |
| 申请号 |
AU20110313665 |
申请日期 |
2011.10.08 |
| 申请人 |
NOVARTIS AG |
发明人 |
SHAH, LIPA;SUTTON, PAUL ALLEN;ZHANG, LIJUN |
| 分类号 |
C07D209/96;A61K31/4025;A61K31/403;A61K31/437;A61K31/4439;A61K31/496;A61K31/497;A61K31/5377;A61K31/7036;A61K31/7056;A61K31/7076;A61K31/7105;A61K31/713;A61K38/13;A61K38/20;A61K38/21;A61P31/20;A61P31/22;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D405/14;C07D417/14;C07K5/08 |
主分类号 |
C07D209/96 |
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