发明名称 A Diagnostic Kit for HBeAg-Negative Chronic Hepatitis B Using Mutated HBV Core Antigen
摘要 PURPOSE: A kit for diagnosing HBe antigen negative chronic hepatitis type B and liver diseases is provided to effectively diagnose liver diseases. CONSTITUTION: A kit for diagnosing HBe antigen negative chronic hepatitis type B contains a primer having bases of seqeunce numbers 1-4. The kit comprises: a DNA probe having base sequences of sequence numbers 17-24 binding to a gene encoding F38S core antigen protein; a linker which contains oligo(dT)15, -(CH2)6-, and amine group in order; and a solid substrate in which an aldehyde group is attached on the surface and which has aldehyde group on the surface linked to an amine group by Schiff's base reaction.
申请公布号 KR101248427(B1) 申请公布日期 2013.03.28
申请号 KR20100085955 申请日期 2010.09.02
申请人 发明人
分类号 C12N15/11;C12Q1/68;G01N33/576 主分类号 C12N15/11
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