| 发明名称 |
NOVEL PYRROLIDINES AS GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE |
| 摘要 |
The present invention relates to compounds of the general formula: (I) wherein ring B, R1, R2, R3, Z, and L1 are selected independently of each other and are as defined herein, to compositions comprising the compounds, and methods of using the compounds as glucagon receptor antagonists and for the treatment or prevention of type 2 diabetes and conditions related thereto. |
| 申请公布号 |
EP2480077(A4) |
申请公布日期 |
2013.03.27 |
| 申请号 |
EP20100819272 |
申请日期 |
2010.09.16 |
| 申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
GILBERT, ERIC, J.;MILLER, MICHAEL, W.;DEMONG, DUANE EUGENE;STAMFORD, ANDREW, W.;GREENLEE, WILLIAM, J. |
| 分类号 |
A01N43/36;A61K31/40;C07D207/09;C07D207/50 |
主分类号 |
A01N43/36 |
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