| 摘要 |
FIELD: medicine.SUBSTANCE: invention refers to isopropyl ester of (S)-2-{[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-ftor-3-hydroxy-4-methyl-tetrahydrofuran-2-ylmethoxy]-phenoxy-phosphorylamino}-propionic acid and its stereoisomer which may be used for treating viral infections in mammals, a method for preparing it, based compositions and the use thereof for treating viral diseases. The prepared method involves a reaction of the compoundsand,wherein Xrepresents a leaving group.EFFECT: what is presented is the new effective agent for treating the diseases caused by hepatitis A and C, West Nile encephalitis, yellow fever, Aden fever, bovine diarrhoea, Japanese encephalitis viruses, rhinovirus, poliovirus, and an effective method for preparing it.14 cl, 82 ex, 32 tbl |
