Recombinant Herpes Virus and Pharmaceutical Composition Containing The Same

摘要

An object of the present invention is to provide a highly-safe recombinant herpes virus showing high antitumor activity regardless of the kind, grade of malignancy, or growth rate of tumor cells. The present invention provides a recombinant herpes simplex virus and the like constructed to express an ICP6 gene under control of a tumor-specific promoter or tissue-specific promoter on the genome of the virus.