发明名称 |
THE MIRNA-212/132 FAMILY AS A THERAPEUTIC TARGET |
摘要 |
The present invention refers to inhibitors of microRNAs, particularly of microRNAs miR-212 and/or miR-132 for use in medicine, particularly in the diagnosis, treatment or prevention of cardiac disorders, e.g. cardiac hypertrophy-associated or autophagic disorders, and further refers to isolated nucleic acid molecules, particularly microRNAs miR-212 and/or miR-132 and related sequences, for use in medicine, particularly human medicine, more particularly in the diagnosis, treatment or prevention of disorders involving cardiac atrophy and/or dysfunctional autophagy, e.g. cardiac cachexia. |
申请公布号 |
WO2013034653(A1) |
申请公布日期 |
2013.03.14 |
申请号 |
WO2012EP67443 |
申请日期 |
2012.09.06 |
申请人 |
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.;MEDIZINISCHE HOCHSCHULE HANNOVER;THUM, THOMAS;CHOWDHURY, KAMAL;UCAR, AHMET;GUPTA, SHASHI KUMAR |
发明人 |
THUM, THOMAS;CHOWDHURY, KAMAL;UCAR, AHMET;GUPTA, SHASHI KUMAR |
分类号 |
C12N15/113;A61K31/7088;A61K31/713 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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