Derivatives of 3-O-(3',3'-dimethylsuccinyl)-betulinic acid

摘要

The present invention relates to compounds of the following formula (I):
or a pharmaceutically acceptable salt thereof, a stereoisomer or a mixture of stereoisomers in any proportion, in particular a mixture of enantiomers, and particularly a racemate mixture,
in which R represents a (C 1 -C 10 )alkyl group substituted with one or more, preferably one or two, groups chosen from COOH and NHR 1 ,
with R 1 representing a hydrogen atom or a -Alk, -C(O)-Alk or -C(O)O-Alk group, Alk representing a (C 1 -C 6 )alkyl group,
as well as a method for preparing them, and their use as a medicine, notably for treating an infection with a retrovirus such as HIV.