| 摘要 |
Provided is a composition comprising: an AD vehicle comprising a synthetic peptide and a lipid, wherein the synthetic peptide comprises an amino acid sequence represented by the formula KnLm (wherein n represents a number of 4 to 8 and m represents a number of 11 to 20); a carboxyvinyl polymer; and an RSV antigen. When the composition is used as a mucosal vaccine, the composition exhibits a higher antibody-producing ability than those of conventional mucosal vaccines. Consequently, the composition can exhibit an excellent effect of inducing an anti-viral antigen-specific IgA antibody and an anti-viral antigen-specific IgG antibody in a nasal lavage fluid and a serum, respectively, even when the RSV antigen is contained in the composition in an extremely small amount. |
