OXIDATION AND AMINATION OF SECONDARY ALCOHOLS

摘要

The invention relates to a method comprising the following steps: a) providing a secondary alcohol; b) oxidizing the secondary alcohol by bringing said alcohol into contact with an NAD(P)+-dependent alcohol dehydrogenase; and c) bringing the oxidation product of step a) into contact with a transaminase, wherein the NAD(P)+-dependent alcohol dehydrogenase and/or the transaminase are/is a recombinant or isolated enzyme. The invention further relates to a whole cell catalyst for carrying out the method and to the use of such a whole cell catalyst for oxidizing a secondary alcohol.