发明名称 |
Potentiator of activity of anti-cancer agent and use thereof, and biomarker for prediction of prognosis in cancer patient and use thereof |
摘要 |
Disclosed is a means for improving the clinical outcomes of cancer therapy. Specifically disclosed is an activity potentiator comprising a compound capable of inhibiting the expression of RFP (RET finger protein) gene or the activity of RFP as an active ingredient. The activity of an anti-cancer agent having an oxidative stress inducing ability can be potentiated by using the anti-cancer agent in combination with the activity potentiator. Further specifically disclosed are a biomarker useful for the recognition of prognosis in a cancer patient and use of the biomarker. |
申请公布号 |
US8372583(B2) |
申请公布日期 |
2013.02.12 |
申请号 |
US200913060314 |
申请日期 |
2009.08.27 |
申请人 |
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY;TAKAHASHI MASAHIDE;KATO TAKUYA;KIKKAWA FUMITAKA |
发明人 |
TAKAHASHI MASAHIDE;KATO TAKUYA;KIKKAWA FUMITAKA |
分类号 |
C12Q1/68;C07H21/02;C07H21/04 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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