发明名称 |
VECTORS CONDITIONALLY EXPRESSING THERAPEUTIC PROTEINS, HOST CELLS COMPRISING THE VECTORS, AND USES THEREOF |
摘要 |
This invention relates to the field of therapeutics. Most specifically, the invention provides methods of generating conditionally expressing vectors for one or more immunomodulators under the control of a gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals. These vector may be provided to treat a variety of disorders, e.g., neoplastic disorders, through direct injection or through in vitro engineered cells, such as dendritic cells. |
申请公布号 |
EP2550359(A1) |
申请公布日期 |
2013.01.30 |
申请号 |
EP20110760175 |
申请日期 |
2011.03.23 |
申请人 |
INTREXON CORPORATION |
发明人 |
ROETH, Jeremiah F.;REED, Charles C.;CUTHBERTSON, Brandon;CHADA, Sunil;FOGLER, William E. |
分类号 |
C12N15/00;A61K38/19;A61K38/20;A61K38/21;A61K38/44;A61K48/00;C07K14/54;C12N5/0784;C12N15/85;C12N15/86 |
主分类号 |
C12N15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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