| 发明名称 |
IDENTIFICATION OF A WEST NILE VIRUS CD4 T CELL EPITOPE AND USE THEREOF |
| 摘要 |
<p>Described herein is the identification and of a potent West Nile virus (WNV) CD4 positive T cell epitope and its use for increasing the immunogenicity of heterologous flavivirus vaccines, such as dengue virus type 2 (DENV-2) DNA and virus-like particle (VLP) vaccines. Also described are methods for the identification of potent T cell epitopes to enhance immunogenicity of multivalent vaccines.</p> |
| 申请公布号 |
CA2836501(A1) |
申请公布日期 |
2013.01.17 |
| 申请号 |
CA20122836501 |
申请日期 |
2012.07.11 |
| 申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SECRETARY OF THE DEPARTMENT OFHEALTH AND HUMAN SERVICES |
发明人 |
CHANG, GWONG-JEN J.;HUGHES, HOLLY R. |
| 分类号 |
C07K14/18 |
主分类号 |
C07K14/18 |
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