发明名称 |
HALOGENATED PHENOLS FOR DIAGNOSTICS, ANTIOXIDANT PROTECTION AND DRUG DELIVERY |
摘要 |
The present invention provides compositions and methods for the targeted delivery, release and/or formation of a drug compound at a target site(s) within the body of an individual, such as a diseased and/or inflamed tissue in the body of the individual. These compositions may comprise a halogenated phenol ring cleavably linked to a core structure of a drug compound. Due to the variety of substituents that may be utilized in forming the different types of linkages, numerous examples of drug compounds linked to a halogenated phenol ring are proposed. The present invention further provides compositions comprising halogenated phenol starting compounds that do not undergo cleavage during a dehalogenation reaction to form a drug compound in a targeted tissue when administered to an individual. Methods of administering these non-cleaving compounds are further provided.
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申请公布号 |
US2013018026(A1) |
申请公布日期 |
2013.01.17 |
申请号 |
US201213548358 |
申请日期 |
2012.07.13 |
申请人 |
LATHAM KEITH R. |
发明人 |
LATHAM KEITH R. |
分类号 |
A61K31/52;A61K31/09;A61K31/137;A61K31/404;A61K31/4045;A61K31/43;A61K31/573;A61P29/00;A61P31/00;A61P35/00;A61P35/04;C07C43/295;C07C49/825;C07C49/84;C07C69/017;C07C211/27;C07C233/25;C07C317/22;C07C321/26;C07D209/08;C07D209/16;C07D239/22;C07D473/16;C07D491/08;C07D499/00;C07J9/00 |
主分类号 |
A61K31/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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