摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to novel disubstituted phenylpyrrolidines of formula, any stereoisomers thereof or any mixtures of stereoisomers thereof, or N-oxides thereof, or pharmaceutically acceptable salts thereof, where Ar denotes phenyl; Rdenotes F, Cl; Rdenotes F and Cl; Rdenotes H, Me, Et, n-Pr, iso-Pr, n-Bu, iso-Bu, sec-Bu, tert-Bu, cyclopropylmethyl, CFHCHCH-, CFHCHCH-, CFCHCH-, allyl and CHOCHCH-; X denotes F, OH; under the condition that X denotes OH, Rdoes not denote H.EFFECT: compounds are capable of increasing levels of dopamine, norepinephrine and serotonin, which enables their use in treating central nervous system disorders.16 cl, 21 dwg, 69 ex |