| 发明名称 |
QUINAZOLINE DERIVATIVES |
| 摘要 |
The invention concerns quinazoline derivatives of Formula I wherein each of Q1, Z, R1 and Q2 have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours which are sensitive to inhibition of erbB receptor tyrosine kinases.
|
| 申请公布号 |
US2013005727(A1) |
申请公布日期 |
2013.01.03 |
| 申请号 |
US201213608092 |
申请日期 |
2012.09.10 |
| 申请人 |
ASTRAZENECA AB;BRADBURY ROBERT HUGH;HENNEQUIN LAURENT FRANCOIS ANDRE;KETTLE JASON GRANT |
发明人 |
BRADBURY ROBERT HUGH;HENNEQUIN LAURENT FRANCOIS ANDRE;KETTLE JASON GRANT |
| 分类号 |
A61K31/517;C07D491/056;A61K31/496;A61K31/5377;A61P9/10;A61P13/08;A61P17/06;A61P35/00;A61P35/02;A61P43/00;C07D239/94;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D413/14;C07D491/04 |
主分类号 |
A61K31/517 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
