A series of celecoxib derivatives defined by Formula I: were prepared and evaluated for their ability to inhibit the gram-negative bacteria Francisella tularensis. Pharmaceutical compositions including celecoxib derivatives and their use in methods for treating or preventing infection by Francisella tularensis in a subject are described.
申请公布号
US2013005788(A1)
申请公布日期
2013.01.03
申请号
US201213610967
申请日期
2012.09.12
申请人
THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION;CHEN CHING-SHIH;CHIU HAO-CHIEH;KULP SAMUEL;GUNN JOHN S.;SCHLESINGER LARRY S.
发明人
CHEN CHING-SHIH;CHIU HAO-CHIEH;KULP SAMUEL;GUNN JOHN S.;SCHLESINGER LARRY S.