发明名称 |
METHODS AND COMPOSITIONS FOR ENHANCING FERTILITY AND/OR INHIBITING PREGNANCY FAILURE AND RESTORING GLUCOSE TOLERANCE |
摘要 |
Methods and compositions for enhancing fertility and/or inhibiting pregnancy failure, restoring glucose tolerance and/or preventing glucose intolerance and/or maintaining glucose homeostasis and/or inducing or enhancing weight loss, treating dyslipidemia, treating hypertestosteronism or hyperandrogenism, and/or treating type 2 diabetes in an individual in need thereof are provided. These involve compositions that inhibit expression of interferon-gamma (IFN-?) or a downstreamIFN-?-stimulated gene, which is preferably a macrolide immunosuppressant compound. |
申请公布号 |
CA2837359(A1) |
申请公布日期 |
2012.12.06 |
申请号 |
CA20122837359 |
申请日期 |
2012.05.31 |
申请人 |
QUEEN'S UNIVERSITY AT KINGSTON |
发明人 |
ALBAGHDADI, AHMAD J.H.;KAN, FREDERICK W.K. |
分类号 |
A61K31/436;A61P3/00;A61P3/04;A61P3/10;A61P5/28;A61P15/08;C07D491/18 |
主分类号 |
A61K31/436 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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