| 摘要 |
<p>The present invention features processes for preparing compounds, such as (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2- (1 -hydroxy-2-methylpropan-2-yl)- 1H-indol-5 -yl)cyclopropanecarboxamide (Compound 1 ), useful for treating CFTR mediated diseases such as cystic fibrosis.</p> |
| 申请人 |
LEE, ELAINE;VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
LEE, ELAINE CHUNGMIN;TANOURY, GERALD J.;HARRISON, CRISTIAN;LITTLER, BENJAMIN JOSEPH;ROSE, PETER JAMISON;HUGHES, ROBERT MICHAEL;JUNG, YOUNG CHUN;SIESEL, DAVID ANDREW;BELMONT, DANIEL T. |
