| 发明名称 |
PYRROLIDINE DERIVATIVES AS NK-3 RECEPTOR ANTAGONISTS |
| 摘要 |
<p>The present application relates to compounds of formula wherein R1, R2, R3, R4, and n are defined herein or to a pharmaceutically active salt thereof. The present compounds are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).</p> |
| 申请公布号 |
EP2513084(A1) |
申请公布日期 |
2012.10.24 |
| 申请号 |
EP20100790561 |
申请日期 |
2010.12.14 |
| 申请人 |
F.HOFFMANN-LA ROCHE AG |
发明人 |
KNUST, HENNER;KOBLET, ANDREAS;NETTEKOVEN, MATTHIAS;RATNI, HASANE;RIEMER, CLAUS;VIFIAN, WALTER |
| 分类号 |
C07D401/06;A61K31/44;A61P25/28;C07D401/14;C07D403/14;C07D405/14 |
主分类号 |
C07D401/06 |
| 代理机构 |
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