| 摘要 |
<p>The present invention relates to 2'-Cyano Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein B, X, R1, R2 and R3are as defined herein. The present invention also relates to compositions comprising at least one 2'-Cyano Substituted Nucleoside Derivative, and methods of using the 2'-Cyano Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.</p> |
| 申请人 |
MERCK SHARP & DOHME CORP.;GIRIJAVALLABHAN, VINAY;NJOROGE, F. GEORGE;BOGEN, STEPHANE;KEREKES, ANGELA;BENNETT, FRANK;HUANG, YING;NAIR, LATHA;PISSARNITSKI, DMITRI;VERMA, VISHAL;DANG, QUN;DAVIES, IAN;OLSEN, DAVID, B.;STAMFORD, ANDREW;VACCA, JOSEPH, P. |
发明人 |
GIRIJAVALLABHAN, VINAY;NJOROGE, F. GEORGE;BOGEN, STEPHANE;KEREKES, ANGELA;BENNETT, FRANK;HUANG, YING;NAIR, LATHA;PISSARNITSKI, DMITRI;VERMA, VISHAL;DANG, QUN;DAVIES, IAN;OLSEN, DAVID, B.;STAMFORD, ANDREW;VACCA, JOSEPH, P. |
